Welcome to Allergy & Asthma Specialists in Jacksonville, Florida

If you suffer from allergy, sinus or asthma problems, you've come to right place for highly specialized and personal care. We are a physician-led, locally owned practice focused on personalized allergy and asthma care. Our goal is simple: clear answers, thoughtful treatment plans, and a team that is easy to reach when you need us.

  • Board-certified allergy and asthma care for adults and children
  • Clear diagnostic testing and treatment options, including immunotherapy (allergy shots)
  • A consistent team that prioritizes communication, follow-up, and continuity

Our board certified allergists Patrick DeMarco, MD and Thomas Lupoli, DO have years of experience specializing in the complete care of both adult and pediatric allergy, asthma and sinus conditions.

NEED AN ALLERGIST?

Why Choose a Board Certified Allergist

Allergies and asthma can affect sleep, work, school, and overall quality of life. When symptoms are persistent or complicated, it helps to see a specialist who is trained specifically in diagnosing triggers and building an evidence-based plan that fits your life.

At Jax Allergy, our board-certified allergists focus on:

  • Getting to the root cause of symptoms, not just short-term relief

  • Explaining options clearly so you can make informed decisions

  • Creating plans designed for long-term control and better day-to-day breathing

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ALLERGY & ASTHMA TREATMENTS

We Specialize In:

Allergy and asthma symptoms are not one-size-fits-all. We evaluate each patient carefully, then tailor treatment to the pattern of symptoms and likely triggers.

Allergic Rhinitis (Hay fever)

Hay fever is a bit of a misnomer because it isn’t caused by hay itself, nor does it produce a

Asthma

If you have asthma, there’s one thing you can be sure of – you’re definitely not alone.

Sinusitis & Sinus Infection Treatment

Treatment of sinusitis and other sinus infections are a specialty of the doctors at

Food Allergies

A food allergy occurs when the body mistakes a particular food protein as being

Stinging Insect Allergy

For a patient with an allergy to insect bites or insect stings, Florida’s year-round mild weather can be a bit of a double-edged sword.

Drug Allergies & Medication Allergies

A drug allergy or medication allergy is a hypersensitivity condition of the body against

Anaphylaxis Management & Treatment

Anaphylaxis is a serious and potentially fatal allergic reaction. It requires immediate

Eczema

Eczema is a chronic, non-contagious inflammation of the skin characterized by itchy

Hives and Swelling

Hives and swelling are typical symptoms of food allergies, drug allergies

Immune Deficiency

If you have an infection that just keeps coming back, you may have an immune deficiency problem.

Nasal Polyps

Nasal polyps are pearly gray-colored, teardrop-shaped, noncancerous growths

Eye Allergies

Eye allergies are among the most common and most annoying allergies out there.

Immunotherapy

Allergy Shots for Long-Term Relief

mmunotherapy (commonly called allergy shots) is a treatment that helps your immune system become less reactive to specific allergens over time. For many patients, it can reduce symptom severity and the need for ongoing medications.

Who it helps:
Immunotherapy may be a good option for patients who:

  • Have persistent symptoms despite standard treatment

  • Prefer a long-term approach rather than relying only on symptom control

  • Have known triggers such as pollens, dust mites, molds, or pet dander

What you can expect:
We confirm your triggers, discuss whether immunotherapy is appropriate, and outline a step-by-step schedule. Our team will give you clear guidance and ongoing support so you know what to expect at each phase of treatment.

immunotherapy allergy shots

REQUEST AN APPOINTMENT

Fill Out The Form or Call Today!

If you are ready to schedule an evaluation—or you want to learn more about allergy testing or immunotherapy—our team is here to help.

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HEAR FROM OUR DOCTORS

Meet Our Board-Certified Allergy Specialists

Our care is led by board-certified allergy specialists who focus on careful evaluation, clear communication, and treatment plans designed around each patient’s needs.

OUR COMMITMENT

Personalized Care and a Team That Prioritizes Communication

As a locally owned practice, we can stay focused on what patients value most: time to ask questions, consistent follow-up, and a care team that works to make communication straightforward. We aim to provide an experience that feels organized, personal, and steady—especially for patients managing symptoms over time.

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    Personalized Allergy

    and Asthma Care

The sheer numbers of people who suffer from asthma, sinusitis and allergy symptoms are daunting. But when you visit the Allergy & Asthma Specialists of North Florida, we’re concerned with just one person - You. As allergists, we know that there is no such thing as one size fits all medicine. That’s why we believe it’s essential to slow down and take the extra time needed to listen to our patients and learn about their concerns. You can be assured that our doctors will listen and collaborate with you to develop a personalized care plan that fits your unique lifestyle.

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    Best Practices

Our doctors are board-certified by the American Board of Allergy & Immunology. This means you are cared for by doctors who have met the highest, nationally recognized standards for education, knowledge and expertise in the field of allergy, asthma and immunology. We are committed to providing the best medical practices to our patients through life-long learning. We stay current in our field by participating in continuing medical education, conferences, and review of the latest medical literature.

FREQUENTLY ASKED QUESTIONS

Don't see your question below?

Contact us today and someone will reach out shortly.

Visit our Frequently Asked Questions page for more commonly asked allergy and asthma questions.

Allergy and Asthma Specialists Locations

Our North Florida Offices

We serve patients across Jacksonville and surrounding communities. Choose the most convenient location and request an appointment.

St. Johns Town Center

  • 2804 St. Johns Bluff Rd. S., Suite 202
  • Jacksonville, FL 32246
  • 904-730-4870

Orange Park

  • 1825 Kingsley Ave Suite 320
  • Orange Park, FL 32073
  • 904-730-4870

Mandarin

  • 12276 San Jose Blvd. Suite #733
  • Jacksonville, FL 32223
  • 904-730-4870

Dunn Ave.

  • 2255 Dunn Ave. Suite 205
  • Jacksonville, FL 32218
  • 904-730-4870

TESTIMONIALS — WHAT OUR PATIENTS SHARE ABOUT THEIR EXPERIENCE

Meet Our Patients

We value long-term relationships, clear guidance, and care that feels personal. Here are a few words patients have shared about their visits.

Dr. DeMarco has cared for my children's asthma and allergy issues. We feel very blessed to have a doctor that really cares about our family and has given such excellent medical advice.

Vitals.com Review

Love the staff and adore Dr. LUPOLI!! Everyone is always so concerned about the well being of the patients. If you are looking for a specialist in Jacksonville I highly recommend you check them out 

KM

Thank you to the staff and doctors for treating my allergies. The staff is always positive, helpful and professional. The doctors are positive and upbeat taking care to inform me of medical needs.

JP

Dr. DeMarco has cared for my children's asthma and allergy issues. We feel very blessed to have a doctor that really cares about our family and has given such excellent medical advice.

Vitals.com Review

Love the staff and adore Dr. LUPOLI!! Everyone is always so concerned about the well being of the patients. If you are looking for a specialist in Jacksonville I highly recommend you check them out 

KM

Thank you to the staff and doctors for treating my allergies. The staff is always positive, helpful and professional. The doctors are positive and upbeat taking care to inform me of medical needs.

JP

READY TO TAKE THE NEXT STEPS?

Schedule an appointment to discuss symptoms, testing, and treatment or view our allergy shots & testing page: